nclusion, increasing die LD and increasing conditioning temperature improved PDI. Starch gelatinization was increased when diets were pelleted at the highest conditioning temperature of 85 °C, and EFC diets resulted in greater starch gelatinization than conventional corn.Growing crossbred steers [n = 80, initial body weight (BW) = 274 kg, SD = 21] were used to evaluate the effect of ad libitum and limit-fed intakes on methane (CH4) production. Two treatments with four pens per treatment (10 steers per pen) were evaluated in a randomized block designed experiment, with BW as a blocking factor. Treatments included feeding the same diet at ad libitum intake or limit fed at 75% of ad libitum intakes. Diet consisted of 45% alfalfa, 30% sorghum silage, 22% modified distillers grains plus solubles, and supplement at 3% on a dry matter (DM) basis. This trial was followed by a finishing trial (n = 80; initial BW = 369 kg; SD = 25) to evaluate the effects of dietary corn oil on CH4 production. Two treatments with four pens per treatment (10 steers per pen) were used in a randomized complete block designed experiment. Cattle were rerandomized and blocked by BW within the previous treatment. Treatments consisted of a control diet (CON) containing 66% corn, 15% wet distillers grains plus .01) by 17% for OIL-fed cattle compared to CON-fed cattle when expressed as grams of CH4 per kilogram of ADG. Feeding corn oil at 3% of diet DM reduced enteric CH4 production (grams per day) by 15%, which was only partially explained by a 3% decrease in DMI. Overall, a decrease in CH4 was observed when intake is limited in growing cattle and when corn oil is added in finishing diets.Cellulose and beet pulp have been commonly used in the pet food industry to increase the dietary fiber content of cat foods. However, pet food companies seek alternatives to these so-called byproducts. Miscanthus grass is grown for its fiber content and may serve as an alternative to traditional fibrous ingredients. The objectives of this study were to determine the effects of fiber sources on extrusion processing and kibble structure of cat foods. Three replicate batches of a complete and balanced foods for adult cats at maintenance each containing 10% of Miscanthus grass, cellulose, or beet pulp was mixed and kibbles were produced on a single-screw extruder. Feed rate, preconditioner water and steam, extruder screw speed, extruder water and steam addition, and knife speed were adjusted to achieve a wet bulk density of 330 g/L. After extrusion, kibbles were dried at 115.5 ºC to less than 10% moisture. Dried kibbles were coated with chicken fat and flavor enhancer. No effects due to fiber source were reported for extrusion parameters or kibble measurements (P &gt; 0.05) with the exception of compression energy, wherein kibbles produced with cellulose required more energy to compress than those containing beet pulp (6,917 N mm vs. https://www.selleckchem.com/products/vt103.html 3,591 N mm, respectively). In conclusion, tested fiber sources had no impact on extrusion parameters and most kibble characteristics. Kibbles containing cellulose required more energy to compress than kibbles containing beet pulp. Miscanthus grass could be used as an alternative to traditional fiber sources used to produce cat foods.Piglets experience a rapid decrease in body temperature immediately after birth, increasing the risk of mortality. The objective of this study was to determine the effect of drying and/or warming piglets at birth on rectal temperature over the first 24 h after birth. The study was carried out at a commercial sow facility using a completely randomized design with four treatments (applied to piglets at birth) Control (no drying or warming), Desiccant (dried using a desiccant), Warming Box (placed in a box under a heat lamp for 30 min), and Desiccant + Warming Box (both dried and warmed as above). Farrowing pens had one heat lamp, temperatures under which were similar to the warming box (35 °C). A total of 68 litters (866 piglets) were randomly allotted to a treatment at the birth of the first piglet. At birth, each piglet was identified with a numbered ear tag and weighed; rectal temperature was measured at 0, 10, 20, 30, 45, 60, 120, and 1,440 min after birth. Data were analyzed using a repeated-measures modeltures between 10 and 120 min after birth, with the combination of the two interventions having the greatest effect, especially for low birth weight piglets.Piglets are born wet, and evaporation of that moisture decreases body temperature, increasing the risk of mortality. The objective of this study was to compare the effect of two commercially applicable methods for drying piglets at birth on piglet rectal temperature over 24 h after birth. The study was carried out in standard commercial farrowing facilities with 52 litters, using a completely randomized design with three Drying Treatments Control (not dried); Desiccant (dried at birth using a cellulose-based desiccant); Paper Towel (dried at birth using paper towels). Litters were randomly allotted to treatments at the birth of the first piglet. At birth, piglets were individually identified, and the treatment was applied. Rectal temperature was measured at 0, 10, 20, 30, 45, 60, 120, and 1,440 min (24 h) after birth. Data were analyzed using a repeated measures model with PROC MIXED of SAS, with litter as the experimental unit and piglet a subsample of the litter. The model included the fixed effects of treao Drying Treatments at 60 min after birth. These results suggest that drying piglets at birth is an effective method to reduce rectal temperature decline in the early postnatal period, especially for low birth weight piglets.Our objective was to validate the NSABP 8-gene trastuzumab-benefit signature, developed and initially validated in NRG Oncology/NSABP B-31 in Alliance/NCCTG N9831. The B-31 and N9831 trials demonstrated the benefit of adding trastuzumab to chemotherapy in the adjuvant setting for HER2+ breast cancer patients. NSABP investigators utilized gene expression profiles of N9831 patients (N?=?892) to blindly assign patients to large-, moderate-, or no-trastuzumab benefit groups and then NCCTG investigators assessed the degree of trastuzumab benefit using Cox models adjusted for age, nodes, estrogen receptor/progesterone receptor status, tumor size, and grade. Hazard ratios and 2-sided P values for recurrence-free survival of the predicted large- (n?=?387), moderate- (n?=?401), and no-benefit (n?=?104) groups, based on the 8-gene signature were 0.47 (95% CI?=?0.31 to 0.73, P less then .001), 0.60 (95% CI?=?0.39 to 0.92, P = .02), and 1.54 (95% CI?=?0.59 to 4.02, P = .38), respectively (Pinteraction = .02), providing validation of the 8-gene signature in an independent study.